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AI Cannot Fix Irreproducible Biology
A new Nature Biotechnology argument for reference materials as common calibrators in multiomics points to a deeper problem: AI-ready biology needs not just more data, but reproducible measurements…
10 Sep 202610 min read
Science
From Sewage to Sequence to Decision: The Missing Evidence Layer in Wastewater Genomic Surveillance
As wastewater genomic surveillance expands from a pandemic-era experiment into permanent infrastructure, a new problem emerges: preserving the evidence chain between the environmental sample, the analytical result and…
8 Sep 202622 min read
Science
At the Wildlife-Livestock Boundary, Genomic Data Needs a Provenance Trail
A new Microbiome study mapped viral sharing between giant pandas, wildlife and livestock in southwestern China, and found that 95.93% of RNA viruses detected could not even be…
4 Sep 202614 min read
Science
When AI Starts Designing Biology, Who Owns the Evidence Chain?
A new $95 million AI BioDesign initiative will put AI models and physical biology experiments into a continuous feedback loop. When an AI-designed molecule reaches the lab, can…
4 Sep 202612 min read
Science
A Million Cattle Records and One Important Question: Can We Reproduce the Evidence?
A study of over a million Australian feedlot cattle found the strongest predictor of respiratory-disease death was set before the animal ever arrived. What it takes to trust…
3 Sep 202614 min read
Science
Sequencing Is the Beginning, Not the End: Building an Evidence Chain for Genomic Surveillance
A PAHO/WHO regional bioinformatics course brought specialists from 11 countries together in Panama City to train on genomic surveillance. Its real lesson: a sequence is only the beginning…
3 Sep 202610 min read
Science
A Virus Hidden in a Book: What 3,500 Years of Sheep Pox Can Tell Us About the Ancient BioChain
Researchers recovered 3,500-year-old sheeppox virus DNA from archaeological remains and medieval manuscripts — some of it from parchment itself. What that reveals about ancient pathogens is also a…
3 Sep 202613 min read
Science
AI Can Analyse the Genome. Can We Reproduce What It Did?
A new deep-learning method for calling cancer variants from long-read sequencing shows how powerful AI-assisted genomics is becoming — and why the provenance chain now has to cover…
30 Aug 202615 min read
Science
The £££ Problem in Genomic Surveillance: What Happens When Sequencing Becomes Cheap Enough to Deploy Everywhere?
A new £12.47-per-sample sequencing method from the Wellcome Sanger Institute shows genomic surveillance can get radically cheaper. What happens to the infrastructure around it once it does?
12 Jul 202616 min read
Science
700,000 Genomes Are Not Enough: The Data Infrastructure Behind Genomic Surveillance
Denmark analysed 738,944 SARS-CoV-2 genomes and found 303 persistent infections — but only because the sequences stayed linked to health records, timing and each other. What that says…
20 Jun 202614 min read